ONX-0914
Produktgrößen
1 mg
£150,00
10-5885-1MG
5 mg
£201,00
10-5885-5MG
Über dieses Produkt
- SKU:
- 10-5885
- Zusätzliche Namen:
- PR-957
- CAS Number:
- 960374-59-8
- Weitere Details:
- ONX-0914 (960374-59-8) is a selective inhibitor of the LMP7 subunit of the immunoproteasome (IC50 = 65 nM for mouse) which is the chymotrypsin-like subunit.1 Treatment with ONX-0914 resulted in suppression of Th1 and Th17 cells but enhancement of regulatory T cell differentiation in mouse models of induced colitis.2 ONX-0914 retards rheumatoid arthritis progression3, ameliorates diabetic cardiomyopathy4 and attenuates atherosclerosis and metabolic syndrome in mice5.
- Immunogen:
- Proteasome
- Molekulargewicht:
- 580.68
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors