BMH-21
Produktgrößen
5 mg
£151,00
10-5688-5MG
25 mg
£253,00
10-5688-25MG
Über dieses Produkt
- SKU:
- 10-5688
- CAS Number:
- 896705-16-1
- Weitere Details:
- A planar heterocyclic DNA intercalator that inhibits RNA polymerase I (Pol I), IC50 = 0.6 uM in U2OS cells, but not Pols II or III, blocking transcription elongation without inducing the DNA damage response.1-3 Inhibition disengages Pol I from chromatin, resulting in proteasome-dependent destruction of Pol I subunit RPA194.4 At nanomolar concentrations it also activates p53 in A375 cells.5
- Immunogen:
- DNA|RNA|Transcription factor
- Molekulargewicht:
- 360.42
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
- Sell Sheet 2:
- View Sell Sheet Here