10074-G5
Produktgrößen
5 mg
£153,00
10-5627-5MG
25 mg
£214,00
10-5627-25MG
Über dieses Produkt
- SKU:
- 10-5627
- CAS Number:
- 413611-93-5
- Weitere Details:
- Inhibits c-Myc by disrupting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity.1 10074-G5 binds to the c-Myc bHLHZip domain with Kd=2.8 mM.1 It was cytotoxic in C-Myc-overexpressing cell lines (IC50s = 13 to 15 mM) but was not active in vivo due to rapid metabolism.2 10074-G5 is a useful tool to probe for involvement of c-Myc involvement in cellular processes.3,4 Binds to and sequesters the intrinsically disordered amyloid-B Beta (AB Beta) in its monomeric soluble state and rescues a C. elegans model of AB Beta-associated toxicity.5
- Immunogen:
- Transcription factor
- Molekulargewicht:
- 332.32
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here