GSK4112
Produktgrößen
5 mg
£153,00
10-5493-5MG
25 mg
£243,00
10-5493-25MG
Über dieses Produkt
- SKU:
- 10-5493
- Zusätzliche Namen:
- SR-6452
- CAS Number:
- 1216744-19-2
- Weitere Details:
- Selective Rev-ErbA Alpha agonist (EC50=250 nM).1,2 It induces circadian clock phase shifts in isolated primary lung fibroblasts as well as in lung slices (10 uM).1 GSK4112 showed an inhibitory effect on the amplitude of circadian oscillations and caused an arrhythmic expression of canonical clock genes.3 In murine RAW264 macrophages it suppressed inflammatory functions via repressing Ccl2 expression.4 It protected RANKL-induced bone loss via inhibition of osteoclast differentiation in vivo.5
- Immunogen:
- Transcription factor
- Molekulargewicht:
- 396.89
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Datenblatt des Herstellers:https://focusbiomolecules.com/gsk4112-rev-erb%ce%b1-agonist/