Ponatinib
Produktgrößen
5 mg
£149,00
10-5064-5MG
25 mg
£214,00
10-5064-25MG
Über dieses Produkt
- SKU:
- 10-5064
- Zusätzliche Namen:
- AP-24534
- CAS Number:
- 943319-70-8
- Weitere Details:
- Highly potent pan-Bcr-Abl and multikinase inhibitor, suppressing the activity of native Bcr-Abl (IC50=0.37 nM) as well as the mutants T315I (IC50=2 nM), Q252H (IC50=0.44 nM), Y253F (IC50=0.3 nM), M351T (IC50=0.3 nM) and H396P (IC50=0.34 nM).1 Also inhibits PDGFR, c-Src and c-Kit (IC50=1.1, 5.4 and 12.5 nM respectively)2 as well as FGFR-mediated signaling (IC50<40 nM)3. Protects against influenza A virus-induced death by suppressing cytokine storm in mouse models.4
- Immunogen:
- Kinase
- Molekulargewicht:
- 532.56
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors