STING Degrader 1
Produktgrößen
1 mg
£206,00
10-5001-1MG
5 mg
£291,00
10-5001-5MG
Über dieses Produkt
- SKU:
- 10-5001
- Zusätzliche Namen:
- SP23
- CAS Number:
- 2762552-74-7
- Weitere Details:
- STING degrader 1 (2762552-74-7) is a CRBN-based PROTAC degrader that recruits the cereblon-containing E3 ubiquitin ligase to direct the proteasomal degradation of the Stimulator of Interferon Genes (STING). This degrader was designed by coupling C-170, a small molecule STING inhibitor with pomalidomide via a C-6 linker. It selectively degrades STING with a DC50=3.2 uM.1 It displays antiinflammatory activity in a cisplatin-induced acute kidney injury mouse model.1
- Immunogen:
- PROTAC®|STING
- Molekulargewicht:
- 699.68
- Physischer Zustand:
- Yellow to beige solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules