Telaprevir
Produktgrößen
5 mg
£149,00
10-4929-5MG
25 mg
£195,00
10-4929-25MG
Über dieses Produkt
- SKU:
- 10-4929
- Zusätzliche Namen:
- VX-950
- CAS Number:
- 402957-28-2
- Weitere Details:
- Hepatitis C NS3/4A protease inhibitor that is in clinical use for genotype 1 infections (IC50 = 354 nM genotype 1b replicon cells; IC50 = 280 nM human fetal hepatocytes infected with genotype 1a HCV-positive patient sera).1-3 It has been shown to inhibit SARS-CoV2 proteases MPro (IC50 = 15 uM)4 and 3CLPro (IC50 = 56 uM)5. Telaprevir is also an allosteric inhibitor of DnaK, the bacterial homolog of Hsp70. It enhanced the efficacy of aminoglycoside antibiotics and reduced resistance to the tuberculosis drug rifampin.6
- Immunogen:
- Protease
- Molekulargewicht:
- 679.86
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors