NR2E3 agonist 11a
Produktgrößen
5 mg
£197,00
10-4866-5MG
25 mg
£411,00
10-4866-25MG
Über dieses Produkt
- SKU:
- 10-4866
- CAS Number:
- 911211-69-3
- Weitere Details:
- 11a is an agonist of the photoreceptor-specific nuclear receptor (NR2E3; PNR; RNR), found in rod photoreceptor cells (EC50 = 141 nM B Beta-lactamase assay; 35 nM NCOR assay).1 An interesting tool for targeting age-related macular degeneration. 11a was able to increase p53 activation in uterine cancer tumors suggesting NR2E3 agonism as a new anti-cancer strategy.2 A previous study found that cytotoxicity of 11a was due to G1/S phase cell cycle arrest rather than NR2E3 agonism.3
- Immunogen:
- Transcription factor
- Molekulargewicht:
- 430.89
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules