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5 mg
£158,00
10-4852-5MG
25 mg
£281,00
10-4852-25MG
Über dieses Produkt
SKU:
10-4852
CAS Number:
2243736-45-8
Weitere Details:
FB23-2 is an inhibitor (IC50 = 2.6 uM) of the mRNA m6A demethylase fat-mass- and obesity-associated protein (FTO).1 Displays significant anti-proliferative activity in NB4 (IC50 = 0.8 uM) and MONOMAC6 (IC50 = 1.5 uM) cells. Selective against the RNA demethylase ALKB5. FB23-2 induced myeloid differentiation and apoptosis in acute myeloid leukemia cells. FB23-2 suppressed the proliferation and migration of hepatocellular carcinoma cells via suppressing the expression of the kinase ERBB3 and human tubulin beta class Iva (TUBB4A).2
Immunogen:
Nucleic acid methylation|RNA
Molekulargewicht:
392.24
Physischer Zustand:
Solid
Reinheit:
98%
Aufreinigung:
HPLC Purified
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
Sell Sheet 1:
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Sell Sheet 2:
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