WP1066
Produktgrößen
10 mg
£177,00
10-4831-10MG
50 mg
£334,00
10-4831-50MG
Über dieses Produkt
- SKU:
- 10-4831
- CAS Number:
- 857064-38-1
- Weitere Details:
- WP1066 (857064-38-1) is an inhibitor of the JAK2/STAT3 pathway as well as STAT5 and AKT.1,2,3 It downregulated Bcl-XL, Mcl-1, and c-myc while activating Bax and inducing apoptosis.1 Active against human malignant glioma U87-MG (IC50 = 5.6uM) and U373-MG (IC50 = 3.7uM) cells. Enhances T-cell cytotoxicity via inhibition of regulatory T-cells.4,5 WP1066 abrogated PD-L1 expression in lymphoma cell lines.6
- Immunogen:
- Kinase|Transcription factor
- Molekulargewicht:
- 356.22
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here