Volasertib
Produktgrößen
5 mg
£168,00
10-4818-5MG
25 mg
£286,00
10-4818-25MG
Über dieses Produkt
- SKU:
- 10-4818
- Zusätzliche Namen:
- BI 6727
- CAS Number:
- 755038-65-4
- Weitere Details:
- Volasertib is an extremely potent and selective inhibitor (IC50's: Plk1= 0.87 nM, Plk2 = 5 nM, Plk3 = 56 nM) of Polo-like kinase 1, a critical controller of multiple essential steps of mitosis.1 It has shown efficacy in multiple solid xenograft tumors models1 and in clinical studies in patients with acute myeloid leukemia2. Volasertib has also been shown to potently inhibit BRD43 (Kd = 79 nM3, IC50's bromodomains 1 and 2 of BRD4 = 300 and 770 nM respectively2).
- Immunogen:
- Bromodomain|Kinase
- Molekulargewicht:
- 618.82
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here