GSK2606414
Produktgrößen
5 mg
£163,00
10-4716-5MG
25 mg
£248,00
10-4716-25MG
Über dieses Produkt
- SKU:
- 10-4716
- CAS Number:
- 1337531-36-8
- Weitere Details:
- Potent (IC50 = 0.4 nM) and selective (against a panel of 294 kinases) inhibitor of protein kinase R-like endoplasmic reticulum kinase (PERK), an important effector of the unfolded protein response (UPR).1 It prevented neurodegeneration in a mouse model of frontotemporal dementia2 and rodent models of Parkinsons disease via modulation of the UPR3. GSK2606414 has been reported to be a potent inhibitor of RIPK1 (IC50 = 18 nM).4 It has also displayed neuroprotective effects in various models of stroke.5-7
- Immunogen:
- Kinase|UPR (Unfolded Protein Response)
- Molekulargewicht:
- 451.44
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors