Necrostatin-34
Produktgrößen
5 mg
£187,00
10-4684-5MG
25 mg
£325,00
10-4684-25MG
Über dieses Produkt
- SKU:
- 10-4684
- Zusätzliche Namen:
- 2-((3-Cyano-6-oxo-4-(p-tolyl)-1,4,5,6-tetrahydropyridin-2-yl)thio)-N-(thiazol-2-yl)acetamide|Nec-34
- CAS Number:
- 375835-43-1
- Weitere Details:
- Necrostatin-34 is a selective inhibitor of RIP1 kinase. IC50s = 667 nM and 134 nM for TNFA Alpha in FAD-deficient Jurkat cells and L929 cells respectively. It binds to a site distinct from that of 7-Cl-O-Nec1 (Focus Cat# 10-4544) locking the enzyme in an inactive conformation. Necrostatin-34 acts synergistically with 7-Cl-O-Nec1 to inhibit necroptosis.
- Immunogen:
- Kinase
- Molekulargewicht:
- 384.47
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here