PB28 dihydrochloride
Produktgrößen
5 mg
£144,00
10-4665-5MG
25 mg
£204,00
10-4665-25MG
Über dieses Produkt
- SKU:
- 10-4665
- CAS Number:
- 172907-03-8
- Weitere Details:
- PB28 is a very potent high affinity (Ki = 5.3 nM1, 0.34 nM2) sigma 2 agonist. Selective for sigma 2 over sigma1 (approx 30-40x).1,2 PB28 inhibited cell growth in MCF7 and MCF7 ADR breast cancer cells and displayed strong synergism with doxorubicin.3 PB28 potently inhibited Kv2.1 currents in a sigma-independent manner.4 PB28 was recently found to have potent (IC50 = 280 nM) anti-SARS-CoV2 activity.5
- Immunogen:
- ER/Golgi|Ion channel
- Molekulargewicht:
- 443.50
- Physischer Zustand:
- Solid
- Reinheit:
- 99%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Biomaterials: Ligands
- Sell Sheet 1:
- View Sell Sheet Here