AE 51310
Produktgrößen
5 mg
£149,00
10-4655-5MG
25 mg
£281,00
10-4655-25MG
Über dieses Produkt
- SKU:
- 10-4655
- CAS Number:
- 433966-92-8
- Weitere Details:
- AE 51310 is a potent antagonist of the GPCR OPN4/melanopsin (Ki = 0.096 nM human OPN4).1 OPN4 regulates circadian rhythms, pupil functions, melatonin expression, cognition, and sleep. OPN4 has been found to bind G11 in lung cancer cells modulating PKC activation leading to activation of BRAF/MEK/ERK signaling pathways. AE 51310 decreased the growth and proliferation of both LG17 and LG55 lung cancer tumors in mouse xenograft models.
- Immunogen:
- OPN4/Melanopsin antagonist
- Molekulargewicht:
- 338.24
- Physischer Zustand:
- Solid
- Reinheit:
- 99%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors