VU0134992
Produktgrößen
5 mg
£144,00
10-4651-5MG
25 mg
£204,00
10-4651-25MG
Über dieses Produkt
- SKU:
- 10-4651
- CAS Number:
- 755002-90-5
- Weitere Details:
- VU0134992 is a blocker of the inward rectifier potassium channel Kir4.1 (IC50 = 970 nM).1 It also inhibits Kir3.1/3.2, Kir3.1/3.4, and Kir4.2 with similar potency. VU0134992 induced diuresis, natriuresis, and kaliuresis in Sprague-Dawley rats suggesting therapeutic blood pressure lowering potential. It reduced polymyxin-induced nephrotoxicity in cell culture and mouse explant kidney tissue.2
- Immunogen:
- Ion channel
- Molekulargewicht:
- 411.38
- Physischer Zustand:
- Off-white/tan solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here