Wnt-C59
Produktgrößen
5 mg
£149,00
10-4605-5MG
25 mg
£195,00
10-4605-25MG
Über dieses Produkt
- SKU:
- 10-4605
- CAS Number:
- 1243243-89-1
- Weitere Details:
- Wnt-C59 is a potent (IC50 = 74 pmol/L) inhibitor of Porcupine (PORCN), a Wnt-acyltransferase. Blockage of Wnt-acyltransferase prevents secretion of all Wnt isoforms. It was able to block progression of mammary tumors in MMTV-WNT1 transgenic mice.1 Wnt-C59 strongly inhibited the growth of intestinal neoplasia in RZ-mutant mice. Wnt-C59 was able to efficiently differentiate pluripotent stem cells into cortical neurons (CTIP2+/COUP-TF1). Wnt-C59 was also able to dramatically attenuate kidney fibrosis via inhibition of collagen mRNA expression and expression of inflammatory cytokines.
- Immunogen:
- Acyltransferase
- Molekulargewicht:
- 379.46
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
- Sell Sheet 2:
- View Sell Sheet Here