L-Buthionine Sulfoximine
Produktgrößen
100 mg
£149,00
10-4572-100MG
250 mg
£187,00
10-4572-250MG
Über dieses Produkt
- SKU:
- 10-4572
- CAS Number:
- 5072-26-4
- Weitere Details:
- Buthionine sulfoximine is an irreversible inhibitor of G Gamma-glutamylcysteine ligase (GCL). GCL is the first enzyme of the cellular glutathione biosynthetic pathway. Dysregulation of glutathione homeostasis is involved in many diseases including cancer, diabetes, neurodegenerative disorders and HIV/AIDS.1 Most disease states involve decreased glutathione synthesis, however, in cancer, it is increased supporting cellular proliferation and protecting cancer cells. Pharmacological inhibition of GCL has been examined as a potential cancer treatment.2-4
- Immunogen:
- Glutathione
- Molekulargewicht:
- 222.31
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors