Ruxolitinib
Produktgrößen
5 mg
£163,00
10-4511-5MG
10 mM (in 1 ml DMSO)
£163,00
10-4511-10MM(IN1MLDMSO)
25 mg
£195,00
10-4511-25MG
Über dieses Produkt
- SKU:
- 10-4511
- Zusätzliche Namen:
- INCB 018424
- CAS Number:
- 941678-49-5
- Weitere Details:
- Potent and selective JAK1&2 inhibitor, IC50s=2.7, 4.5 and 322 nM forJAK1, JAK2 and JAK3 respectively.1 Blocks IL-6 signaling (IC50=281 nM) and proliferation of JAK2V617F+ Ba/F3 cells (IC50=127 nM).2 Inhibits the proinflammatory secretome of senescent cells.3 The JAK1 S646P mutant is highly sensitive to ruxolitinib.4 Clinically useful cancer chemotherapeutic.
- Immunogen:
- Kinase
- Molekulargewicht:
- 306.37
- Physischer Zustand:
- Solid
- Reinheit:
- 99%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors