Ervogastat
Produktgrößen
5 mg
£197,00
10-4459-5MG
25 mg
£431,00
10-4459-25MG
Über dieses Produkt
- SKU:
- 10-4459
- Zusätzliche Namen:
- PF-06865571
- CAS Number:
- 2186700-33-2
- Weitere Details:
- Ervogastat is a potent (IC50 = 17.2 nM) and selective (against DGAT1 and MGATs 1-3) inhibitor of diacylglycerol transferase 2 (DGAT2). It reduced liver and plasma triglyceride levels in Sprague-Dawley rats feed a high fat high cholesterol diet by 49% and 70% respectively.1 Ervogastat displayed efficacy in combination with the ACC inhibitor clesacostat in resolving metabolic dysfunction-associated steatohepatitis (MASH) with liver fibrosis.2
- Molekulargewicht:
- 407.43
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors