SBI-553
Produktgrößen
5 mg
£187,00
10-4449-5MG
25 mg
£358,00
10-4449-25MG
Über dieses Produkt
- SKU:
- 10-4449
- CAS Number:
- 1849603-72-0
- Weitere Details:
- SBI-553 is a potent, brain penetrant, and orally bioavailable allosteric modulator of neurotensin receptor 1 (NTSR1; EC50 = 340 nM)).1 It acts as a B Beta-Arrestin-biased agonist and selectively antagonizes G protein signaling conferring profound B Beta-Arrestin bias towards the endogenous ligand.2,3 SBI-553 displayed efficacy in mouse models of psychostimulant abuse without the characteristic undesirable side effects of unbiased NTSR1 agonism. This functionally selective modulation of NTSR1 may be a new therapeutic approach to treating psychostimulant abuse and other chemical and behavioral addictions.
- Immunogen:
- GPCR
- Molekulargewicht:
- 450.56
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here