ZT-1a
Produktgrößen
5 mg
£187,00
10-4402-5MG
25 mg
£363,00
10-4402-25MG
Über dieses Produkt
- SKU:
- 10-4402
- CAS Number:
- 212135-62-1
- Weitere Details:
- ZT-1a is a non-ATP competitive inhibitor (IC50 = 44.3 uM @ 0.01 mM ATP) of SPAK kinase (STK39), a master regulator of cation-Cl- cotransporters.1 It attenuated cerebral edema, protected against ischemic brain damage, and improved post-ischemic neurological outcomes in mouse models of stroke.1,2 ZT-1a showed neuroprotective effects in mouse models of vascular dementia3 and multiple sclerosis4. It inhibited the progression of hepatocellular carcinoma in rodent models and showed synergistic effects with PD-1 antibodies by helping to prevent tumor microenvironment immune exhaustion.5
- Immunogen:
- Kinase
- Molekulargewicht:
- 445.72
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors