Capivasertib
Produktgrößen
5 mg
£158,00
10-4383-5MG
25 mg
£238,00
10-4383-25MG
Über dieses Produkt
- SKU:
- 10-4383
- Zusätzliche Namen:
- AZD5363
- CAS Number:
- 1143532-39-1
- Weitere Details:
- Capivasertib is a potent ATP-competitive pan-Akt inhibitor (IC50s: Akt1 = 3 nM, Akt2 = 8 nM, Akt3 = 8 nM).1,2 It reduced tumor vascular density, decreased influx of myeloid cells, and reduced tumor regrowth in hepatocarcinoma models in conjunction with radiotherapy.3 Capivasertib significantly reduced cancer migration and invasion in a colorectal cancer model.4 It enhanced CAR-T cell activity in B cell lymphoma models.5 FDA approved for the treatment of HR+/HER2-negative breast cancer.
- Immunogen:
- Kinase
- Molekulargewicht:
- 428.92
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors