Buparlisib
Produktgrößen
5 mg
£158,00
10-4325-5MG
25 mg
£272,00
10-4325-25MG
Über dieses Produkt
- SKU:
- 10-4325
- Zusätzliche Namen:
- BKM-120|NVP-BKM120
- CAS Number:
- 944396-07-0
- Weitere Details:
- Potent pan-Class I PI3-kinase inhibitor (IC50's: p110A Alpha = 52 nM, p110B Beta = 166 nM, p110D Delta = 116 nM. P110g = 262 nM).1,2 It inhibited microtubule dynamics at in vitro concentrations >1uM and doses above 50mg/kg in mice.3 Buparlisib lead to a precipitous drop in DNA synthesis in a mouse model of BRCA1-linked triple-negative breast cancer with less affect in normal tissue.4
- Immunogen:
- Cytoskeleton|Kinase
- Molekulargewicht:
- 410.39
- Physischer Zustand:
- Solid
- Reinheit:
- 99%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors