K-975
Produktgrößen
1 mg
£134,00
10-4297-1MG
5 mg
£206,00
10-4297-5MG
Über dieses Produkt
- SKU:
- 10-4297
- CAS Number:
- 2563855-03-6
- Weitere Details:
- K-975 is a covalent inhibitor of YAP/TAZ-TEAD signaling. It binds to the palmitate-binding pocket of TEAD preventing its association with YAP/TAZ.1 K-975 inhibited proliferation of NF2-non-expressing mesothelioma cell lines. K-975 promoted liver progenitor cell to hepatocyte differentiation via suppression of YAP signaling.2 It sensitized YAP-expressing RET-aberrant cancer cells to RET kinase inhibitors.3
- Immunogen:
- Transcription factor
- Molekulargewicht:
- 287.74
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors