H-151
Produktgrößen
10 mg
£163,00
10-4132-10MG
50 mg
£281,00
10-4132-50MG
Über dieses Produkt
- SKU:
- 10-4132
- CAS Number:
- 941987-60-6
- Weitere Details:
- H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice.1 H-151 alleviates microglial dysfunction and a broad spectrum of Alzheimer's disease pathologies in AD mouse models.3
- Immunogen:
- STING
- Molekulargewicht:
- 279.34
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here