LY2603618
Produktgrößen
5 mg
£149,00
10-4123-5MG
25 mg
£238,00
10-4123-25MG
Über dieses Produkt
- SKU:
- 10-4123
- Zusätzliche Namen:
- Rabusertib
- CAS Number:
- 911222-45-2
- Weitere Details:
- LY2603618 is a potent (IC50 = 7nM) and selective (>1000x over Chk2) Checkpoint kinase 1 (Chk1) inhibitor.1 Chk1 is an important regulator of the DNA damage response - combination treatment of LY2603618 with other chemotherapeutic agents significantly increased tumor growth inhibition when compared to chemotherapeutic alone.2,3,4 LY2603618 caused a dramatic suppression of cell growth in MCF-7 and MDA-MB-231 human breast cancer cells via Chk1 inhibition induced upregulation of replication stress caused by oncogenes.5
- Immunogen:
- Kinase
- Molekulargewicht:
- 436.30
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors