N6022
Produktgrößen
5 mg
£158,00
10-4103-5MG
25 mg
£248,00
10-4103-25MG
Über dieses Produkt
- SKU:
- 10-4103
- CAS Number:
- 1208315-24-5
- Weitere Details:
- N6022 is a potent and reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) - IC50 = 20 nM1, 8 nM2. It demonstrated significant efficacy in a mouse models of ovalbumin-induced asthma, chronic obstructive pulmonary disease, and irritable bowel syndrome. N6022 was able to attenuate experimental autoimmune encephalomyelitis (an animal model of multiple sclerosis) via selective inhibition of pro-inflammatory CD4+ cells (TH1/TH17) while upregulating anti-inflammatory subsets of CD4+ cells (TH2/Treg) without causing lymphopenia.3
- Immunogen:
- Glutathione
- Molekulargewicht:
- 414.46
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors