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10 mg
£168,00
10-4066-10MG
50 mg
£267,00
10-4066-50MG
Über dieses Produkt
SKU:
10-4066
CAS Number:
1246525-60-9
Weitere Details:
Agonist of the orphan nuclear receptors RORA Alpha and RORG Gamma.1 It attenuated intrapancreatic pathological changes in mouse models of chronic pancreatitis via restoration of the circadian stabilizing loop.2 SR1078 stimulation of RORA Alpha restored clock protein BMAL1 expression and oscillation and blocked MYCN-mediated neuroblastoma growth.3 It reduced repetitive behavior is a mouse model of autism suggesting a potential therapeutic pathway for the disorder.4 SR1078 treatment lead to an increase in p53 levels and increased apoptosis in HepG2 cells.5
Immunogen:
Retinoid receptor and related|Transcription factor
Molekulargewicht:
431.26
Physischer Zustand:
Solid
Reinheit:
>98%
Aufreinigung:
HPLC Purified
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules