AZD5904
Produktgrößen
5 mg
£177,00
10-4058-5MG
25 mg
£320,00
10-4058-25MG
Über dieses Produkt
- SKU:
- 10-4058
- Zusätzliche Namen:
- TX4
- CAS Number:
- 618913-30-7
- Weitere Details:
- A mechanism-based inactivator of myeloperoxidase (IC50 = 200 nM), reacting with hydrogen peroxide in neutrophils to inactivate the enzyme.1 This prevents production of hypochlorous acid and concomitant oxidative stress. Importantly, neutrophil bactericidal activity was slowed but not stopped. AZD5904 did not inactivate thyroid peroxidase or lactoperoxidase. AZD5904 prevented the onset and reversed established high-fat diet induced microvascular insulin resistance.2 It also alleviated the relaxation defect in hypertrophic induced pluripotent cardiomyocytes via restoration of MYBPC3 phosphorylation, suggesting potential therapeutic value in treating hypertrophic cardiomyopathy.3
- Immunogen:
- Glutathione
- Molekulargewicht:
- 252.29
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors