AZD3965
Produktgrößen
25 mg
£ POA
10-4056-25MG
5 mg
£209,00
10-4056-5MG
Über dieses Produkt
- SKU:
- 10-4056
- CAS Number:
- 1448671-31-5
- Weitere Details:
- AZD3965 is a potent inhibitor (Ki's: 1.6 - 3.2 nM) of monocarboxylate transporter 1 (MCT1) with approximately 6-fold selectivity over MCT2.1 Active in multiple cancer models as monotherapy or in combination with other chemotherapeutics.2 AZD3965 improved CAR-T cell therapy against B-cell malignancies.3 It inhibited lipid biosynthesis and increased tumor infiltration of dendritic and natural killer cells.4 Combination therapy with immune checkpoint blockade suppressed lactate-mediated immunosuppression in the tumor microenvironment.5
- Molekulargewicht:
- 515.51
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors