TETi76 ester
Produktgrößen
10 mg
£173,00
10-4041-10MG
50 mg
£315,00
10-4041-50MG
Über dieses Produkt
- SKU:
- 10-4041
- CAS Number:
- 1451750-73-4
- Weitere Details:
- Cell permeable inhibitor of TET dioxygenases (IC50s: TET1 = 1.5 uM; TET2 = 9.4 uM; TET3 = 8.8 uM), indirect (via cytosine hydroxymethylation) erasers of DNA methylation.1,2 TET2 is frequently mutated in myeloid neoplasms - TET2 inhibition with TETi76 restricted clonal outgrowth and induced apoptosis of TET2 mutants but not normal hematopoietic precursor cells in vitro and in vivo.
- Immunogen:
- DNA|Nucleic acid methylation
- Molekulargewicht:
- 216.23
- Physischer Zustand:
- Oil
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors