iJMJD6
Produktgrößen
5 mg
£173,00
10-4039-5MG
25 mg
£325,00
10-4039-25MG
Über dieses Produkt
- SKU:
- 10-4039
- Zusätzliche Namen:
- WL12
- CAS Number:
- 899548-78-8
- Weitere Details:
- Inhibitor of the arginine demethylase JMJD6 (IC50 = 220 nM) with selectivity over other JmjC domain-containing proteins.1 Exhibited antiproliferative effects in HeLa (EC50 = 1.49 uM), SMCC7721 (EC50 = 9.37 uM), and MCF7 (EC50 = 9.53 uM) cells.2 Displayed no cytotoxicity towards normal cervical, liver, and breast epithelial cells. iJMJD6 significantly suppressed tumor growth in a HeLa, SMCC7721, MCF7, MDA-MB-231, U87, and HCT116 mouse xenograft models.2
- Immunogen:
- Protein demethylase
- Molekulargewicht:
- 277.28
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here