Brequinar sodium
Produktgrößen
10 mg
£158,00
10-3965-10MG
50 mg
£315,00
10-3965-50MG
Über dieses Produkt
- SKU:
- 10-3965
- Zusätzliche Namen:
- DuP-785|NSC 368390
- CAS Number:
- 96201-88-6
- Weitere Details:
- Brequinar sodium is an inhibitor of dihydroorotate dehydrogenase (DHODH)1,2 with IC50's between 0.2 and 5.8 uM in various cell lines3 and 20 nM in isolated enzyme4. It reduced leukemic cell burden, decreased levels of leukemia-initiating cells, and improved survival in human and mouse models of acute myeloid leukemia.4 Brequinar displayed broad antiviral activity against flaviviruses, positive-strand RNA alphaviruses, negative-strand RNA rhabdoviruses, Influenza A and B viruses, and HIV.5,6,7
- Immunogen:
- Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH, ALDH, GDH, IDH, UGDH, DPD, DHPDH, KGDH, PDH, and MDH)
- Molekulargewicht:
- 397.35
- Physischer Zustand:
- Solid
- Reinheit:
- 99%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors