PF-06835919
Produktgrößen
1 mg
£177,00
10-3958-1MG
5 mg
£334,00
10-3958-5MG
Über dieses Produkt
- SKU:
- 10-3958
- CAS Number:
- 2102501-84-6
- Weitere Details:
- PF-06835919 is a potent (IC50 = 10 nM KHK-C; 170 nM KHK-A) inhibitor of ketohexokinase (KHK), the first enzyme in the fructose metabolic cascade.1 It displayed high selectivity against other sugar kinases. PF-06835919 prevented hyperinsulinemia, hypertriglyceridemia, and hepatic steatosis in fructose-fed rats.2 The increased tumor proliferation effect of fructose in CaSki cells was inhibited by PF-06835919.3 An interesting new tool to study metabolic and fatty liver diseases.
- Immunogen:
- Cytochrome/MDR|Sugar kinase
- Molekulargewicht:
- 356.35
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors