PY-60
Produktgrößen
5 mg
£173,00
10-3924-5MG
25 mg
£315,00
10-3924-25MG
Über dieses Produkt
- SKU:
- 10-3924
- CAS Number:
- 2765218-56-0
- Weitere Details:
- PY-60 (2765218-56-0) activates YAP transcriptional activity (EC50 = 1.6 uM) via delocalization of annexin A2 (ANXA2) from cell membranes leading to Hippo inactivation, a key controller of YAP.1 It was able to induce serum-free expansion of MCF10A cells and epidermal keratinocytes and their precursors ex vivo and in adult mice. PY-60 promoted regenerative repair of cutaneous wounds in pig and human models by enabling a pro-proliferative transcriptional program in keratinocytes and dermal cells that accelerated re-epithelization and regranulation of the wound bed.2
- Immunogen:
- Transcription factor
- Molekulargewicht:
- 313.38
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules