Lipofermata
Produktgrößen
10 mg
£163,00
10-3902-10MG
50 mg
£267,00
10-3902-50MG
Über dieses Produkt
- SKU:
- 10-3902
- Zusätzliche Namen:
- CB16.2
- CAS Number:
- 297180-15-5
- Weitere Details:
- Lipofermata is an inhibitor of fatty acid transport protein 2 (FATP2; IC50 = 4.84 uM).1 It does not inhibit glucose transport or the activity of long chain acyl-CoA synthetase. It prevented palmitate-mediated oxidative stress, induction of BiP and CHOP, and cell death in a dose-dependent manner in hsHepG2 and mINS-1E cells suggesting utility in preventing fatty acid-mediated cell death pathways and lipotoxic disease.2 Inhibition was specific for long and very long chain fatty acids but not medium (C6-C10) acids. Lipofermata abrogates lipid transport into melanoma cells and reduces melanoma growth and invasion.3
- Molekulargewicht:
- 360.23
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors