Tafamidis
Produktgrößen
5 mg
£158,00
10-3743-5MG
25 mg
£243,00
10-3743-25MG
Über dieses Produkt
- SKU:
- 10-3743
- Zusätzliche Namen:
- PF-06291826
- CAS Number:
- 594839-88-0
- Weitere Details:
- A potent and selective transthyretin (TTR) kinetic stabilizer. It binds selectively and with negative cooperativity to the two normally unoccupied thyroxine binding sites of the TTR tetramer (Kd = ~2 and ~200 nM)1. Stabilizes wild-type and mutant TTR under varying conditions in vitro (EC50=2.7-3.2 M).1 Clinically useful for the treatment of familial amyloid polyneuropathy2,3 and TTR-related cardiomyopathy4.
- Immunogen:
- UPR (Unfolded Protein Response)
- Molekulargewicht:
- 308.12
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules