ABT-737
Produktgrößen
5 mg
£177,00
10-3661-5MG
25 mg
£286,00
10-3661-25MG
Über dieses Produkt
- SKU:
- 10-3661
- CAS Number:
- 852808-04-9
- Weitere Details:
- Inhibitor of anti-apoptotic proteins from the Bcl family: Bcl-2, Bcl-X(L), and Bcl-w (Ki < 1 nM) that causes regression of solid tumors in mice.1 Senolytic agent which disrupts aberrant p21 expression, inducing apoptosis in senescent cells, and enhancing liver regeneration in mice.2,3 Acts synergistically to reduce cell viability when combined with CDK inhibitor purvalanol A in preclinical models of acute myeloid leukemia (AML).4
- Immunogen:
- Bcl-2
- Molekulargewicht:
- 813.43
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Datenblatt des Herstellers:https://focusbiomolecules.com/abt-737-senolytic-bcl2-inhibitor/