AA43279
Produktgrößen
5 mg
£158,00
10-3503-5MG
25 mg
£243,00
10-3503-25MG
Über dieses Produkt
- SKU:
- 10-3503
- CAS Number:
- 354812-16-1
- Weitere Details:
- Selective Nav1.1activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 uM). In rat hippocampal brain slices it increased the firing activity parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels.1
- Immunogen:
- Ion channel
- Molekulargewicht:
- 248.30
- Physischer Zustand:
- Solid
- Reinheit:
- 97%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here