CLP-3094
Produktgrößen
5 mg
£163,00
10-3382-5MG
25 mg
£301,00
10-3382-25MG
Über dieses Produkt
- SKU:
- 10-3382
- CAS Number:
- 312749-73-8
- Weitere Details:
- GPR142 is highly expressed in the pancreas and immune system and shares 33% homology with GPR1391. Endogenous agonists identified to date include aromatic amino acids such as tryptophan and phenylalanine2. CLP-3094 was identified as a potent and selective GPR142 antagonist with an IC50=2.3 M against 1 mM L-tryptophan. It inhibited insulin secretion from islets induced by L-tryptophan and other agonists and displayed anti-inflammatory activity in a mouse arthritis model.3
- Immunogen:
- GPCR
- Molekulargewicht:
- 304.79
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors