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10 mg
£149,00
10-3361-10MG
50 mg
£195,00
10-3361-50MG
Über dieses Produkt
SKU:
10-3361
CAS Number:
293754-55-9
Weitere Details:
Potent high affinity liver X receptor (LXRA Alpha and B Beta) agonist, EC50~50 nM.1 Upregulates expression of ABCA1, a reverse cholesterol transporter, resulting in inhibition of cholesterol absorption. Inverse agonist at CAR.2 T0901317 was also shown to be an FXR agonist at lower potency than LXR thus appropriate controls must be employed when using this compound as a pharmacological tool.3 Decreases amyloid beta production in a mouse model of Alzheimer's disease.4 Inhibits cellular senescence in endothelial cells.5
Immunogen:
Transcription factor
Molekulargewicht:
481.33
Physischer Zustand:
Solid
Reinheit:
>98%
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules