MDL-28170
Produktgrößen
5 mg
£147,00
10-3005-5MG
25 mg
£243,00
10-3005-25MG
Über dieses Produkt
- SKU:
- 10-3005
- Zusätzliche Namen:
- Calpain Inhibitor III|Z-Val-Phe-CHO
- CAS Number:
- 88191-84-8
- Weitere Details:
- A potent and selective cell permeable calpain inhibitor. Inhibits oxidative damage-induced apoptosis in PC12 cells and capsaicin-induced apoptosis in dorsal root ganglion neurons.1 It penetrates the blood-brain barrier and inhibits brain cysteine protease activity after systemic administration, ameliorating brain damage in a gerbil model of global ischemia.2 Displays neuroprotective effects in neurotrama rodent models.3 Calpain I Ki = 8 nM; Cathepsin B Ki = 24 nM in isolated enzyme assays. IC50 = 0.3 uM in intact cell assay.4
- Immunogen:
- Protease
- Molekulargewicht:
- 382.45
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors