PAC-1
Produktgrößen
5 mg
£129,00
10-2979-5MG
25 mg
£192,00
10-2979-25MG
Über dieses Produkt
- SKU:
- 10-2979
- CAS Number:
- 315183-21-2
- Weitere Details:
- PAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 uM.1 It is less potent at activating procaspase-7, EC50=4.5 uM. It induces apoptosis in a variety of cancer cell lines. The mechanism of activation involves sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate.2 Sensitizes cancer cells to various chemotherapeutic agents.3
- Immunogen:
- Chelator|Protease
- Molekulargewicht:
- 392.49
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules