PLX-4032
Produktgrößen
5 mg
£139,00
10-2928-5MG
25 mg
£190,00
10-2928-25MG
Über dieses Produkt
- SKU:
- 10-2928
- Zusätzliche Namen:
- R7204|Ro 51-85426|Vemurafenib
- CAS Number:
- 918504-65-1
- Weitere Details:
- An ATP-competitive inhibitor of mutant V600E/F and wild type B-Raf, IC50s=31 and 100 nM respectively.1 Induced growth inhibition, G0/G1 arrest and apoptosis in a variety of cancer cell lines, with a B-Raf mutation favoring but not guaranteeing a response.2 Inhibits the growth of B-Raf V600E-positive melanomas in vitro and in vivo.3 Treatment of patients that carry the V600E BRAF mutation resulted in complete or partial tumor regression.4
- Immunogen:
- Kinase
- Molekulargewicht:
- 489.92
- Physischer Zustand:
- Solid
- Reinheit:
- 99%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors