Migalastat
Produktgrößen
1 mg
£139,00
10-2632-1MG
5 mg
£204,00
10-2632-5MG
Über dieses Produkt
- SKU:
- 10-2632
- Zusätzliche Namen:
- 1-deoxygalactonojirimycin|AT1001|DDIG|DGJ|GR181413
- CAS Number:
- 75172-81-5
- Weitere Details:
- Migalastat is a potent, selective, and orally available inhibitor of A Alpha-galactosidase A (IC50= 40 nM).1 It binds to mutant misfolded A Alpha-GalA shifting the folding behavior toward functional active conformation (pharmacological chaperone activity) followed by trafficking to the lysosomes.2 Migalastat is active broadly across species from Drosophila3 to human4. Clinically useful agent for Fabry disease.5
- Immunogen:
- Chaperone|Galactosidase
- Molekulargewicht:
- 199.63
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors