FAK inhibitor 14
Produktgrößen
10 mg
£144,00
10-2547-10MG
50 mg
£224,00
10-2547-50MG
Über dieses Produkt
- SKU:
- 10-2547
- Zusätzliche Namen:
- Y15
- CAS Number:
- 4506-66-5
- Weitere Details:
- Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 uM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo. Induces regression of pancreatic tumors2 and glioblastoma3. Displays antiangiogenic activity4.
- Immunogen:
- Kinase
- Molekulargewicht:
- 284.02
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors