Pazopanib
Produktgrößen
10 mg
£139,00
10-2158-10MG
50 mg
£216,00
10-2158-50MG
Über dieses Produkt
- SKU:
- 10-2158
- Zusätzliche Namen:
- GSK-VEG10003|GW786034B
- CAS Number:
- 444731-52-6
- Weitere Details:
- Inhibits multiple receptor tyrosine kinases including VEGFR1,2 and 3 (IC50s=10, 30, 47 nM respectively) and PDGFRA Alpha, B Beta and c-Kit (IC50s=71, 84, 74 nM respectively) and others such as FGFR.1 The drug targets both the tumor and endothelial cells in a mouse xenograft model of human multiple myeloma.2 It reduces joint pain and inhibits cartilage degeneration in rodent osteoarthritis models.3 VEGF inhibitors such as pazopanib have potential for treatment of neovascular age-related macular degeneration.4 In clinical use for renal cell carcinoma.5
- Immunogen:
- Kinase
- Molekulargewicht:
- 437.52
- Physischer Zustand:
- Solid
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors