Lenalidomide
Produktgrößen
100 mg
£173,00
10-2148-100MG
500 mg
£224,00
10-2148-500MG
Über dieses Produkt
- SKU:
- 10-2148
- Zusätzliche Namen:
- CC-5013
- CAS Number:
- 191732-72-6
- Weitere Details:
- Thalidomide analog which, like thalidomide,1 binds to cereblon which is the substrate recognition component of a cullin-dependent ubiquitin ligase and inhibits its autoubiquitination activity2. Induces degradation of T-cell repressors Ikaros (IKZF1) and Aiolos (IKZF3) leading to T cell activation2. Selective inhibition of IKZF1 and IKZF3 in multiple myeloma cells results in cell death3,4. Cell permeable. Caution: Teratogenic
- Immunogen:
- Molecular glue|Ubiquitin ligase
- Molekulargewicht:
- 259.26
- Physischer Zustand:
- Solid
- Reinheit:
- 98%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- RT
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here
- Sell Sheet 2:
- View Sell Sheet Here