Dovitinib
Produktgrößen
5 mg
£173,00
10-2129-5MG
25 mg
£301,00
10-2129-25MG
Über dieses Produkt
- SKU:
- 10-2129
- Zusätzliche Namen:
- CHIR258|TKI-258
- CAS Number:
- 405169-16-6
- Weitere Details:
- Potent kinase inhibitor. Inhibits FLT3 (IC50 = 1 nM), c-KIT (IC50 = 2 nM), FGFR (IC50 = 8 nM), VEGFR1/2/3 (IC50 = 10 nM), PDGFRB Beta (IC50 = 27 nM), and CSF-1R (IC50 = 36 nM).1 Active in cell culture and in whole animals. Selectively blocks the growth B9 cells transformed by wild type, or activated mutant FGFR3. Induces apoptosis, or sensitizes cells to induction of apoptosis by other means in a variety of cancer cell lines.
- Immunogen:
- Kinase
- Molekulargewicht:
- 392.43
- Physischer Zustand:
- Solid
- Reinheit:
- 99%
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors